Telocinobufagin

Product Specifications

CAS Number

472-26-4

Target

PI3K|||Others|||Akt|||Apoptosis|||ATPase|||PLK|||STAT|||JAK|||mTOR

Related Pathways

Stem Cells|||JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic|||Apoptosis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Others|||Cell Cycle/Checkpoint|||Membrane transporter/Ion channel|||Angiogenesis

Purity

0.9974

Bioactivity

1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice challenged with live S. typhimurium. 3. Telocinobufagin has immunomodulatory activity, can enhance a Th1 immune response to control intracellular infections, could be developed as a novel immunotherapeutic agent to treat cancer and other immune-mediated diseases.