BMS-986143
Product Specifications
CAS Number
1643372-95-5
Target
Others|||BTK
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Others
Bioactivity
BMS-986143, an orally active, reversible BTK inhibitor with an IC50 value of 0.26 nM, is designed for autoimmune disease research. Additionally, it targets TEC, BLK, BMX, TXK, FGR, YES1, and ITK, exhibiting IC50s of 3 nM, 5 nM, 7 nM, 10 nM, 15 nM, 19 nM, and 21 nM, respectively [1].
Smiles
ClC=1C(=C2C(=C(C(N)=O)C1)NC=3C2=CC=C(C(C)(C)O)C3)C4=C(C)C(=CC=C4)N5C(=O)N6C(=CC5=O)C(Cl)=CC=C6
Molecular Formula
C31H24Cl2N4O4
Molecular Weight
587.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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