ALK-IN-12
Product Specifications
Target
Others|||ALK
Related Pathways
Others|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
ALK-IN-12 is a highly potent and orally active inhibitor of anaplastic lymphoma kinase (ALK), demonstrating an exceptional IC50 value of 0.18 nM. Additionally, ALK-IN-12 displays inhibitory activity against insulin-like growth factor 1 receptor (IGF1R) and insulin receptor (InsR), with IC50 values of 20.3 nM and 90.6 nM, respectively. Notably, its antitumor effects have been observed, making it a promising compound for targeted cancer therapy.
Smiles
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1)N1CCN(C)CC1
Molecular Formula
C24H30ClN6O2P
Molecular Weight
500.97
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/A1844FBD-6899-424E-BAF2-33243744D846/T38584
CAS Number
1197958-53-4
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