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Guselkumab

Product Specifications

CAS Number

1350289-85-8

Target

IL Receptor|||Interleukin

Related Pathways

Immunology/Inflammation

Purity

0.9897

Bioactivity

Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab can inhibit the production of cytokines downstream of IL-23 signaling pathway, and can be used in the study of psoriatic arthritis.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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