BE-24566B
Product Specifications
CAS Number
149466-04-6
Target
Others|||Endothelin Receptor|||Antibacterial
Related Pathways
Others|||Microbiology/Virology|||GPCR/G Protein
Bioactivity
BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, andS. thermophilus (MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 ?g/ml, respectively) . BE-24566B is an endothelin (ET) receptor antagonist (IC50s = 11 and 3.9 ?M for ETAand ETBreceptors, respectively) .2
Smiles
[H][C@]12O[C@](C)(Cc3cc4c(C(=O)c5c(O)cc(O)cc5C4(C)C)c(O)c13)Oc1cc(O)cc(C)c21|TLB:23:25:34.27.26:2,28:27:2:25.5.6,32:34:2:25.5.6|
Molecular Formula
C27H24O7
Molecular Weight
460.482
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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