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Givinostat

Product Specifications

Target

Apoptosis|||IL Receptor|||STAT|||HDAC|||TNF

Related Pathways

Stem Cells|||Immunology/Inflammation|||Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||JAK/STAT signaling

Purity

0.9856

Bioactivity

Givinostat (ITF-2357) is an HDAC inhibitor with IC50 values of 198 nM for HDAC1 and 157 nM for HDAC3.

Smiles

CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(cc3)C(=O)NO)ccc2c1

Molecular Formula

C24H27N3O4

Molecular Weight

421.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/5B98EB1D-464B-48ED-BD66-2812D5C3A008/T36629

CAS Number

497833-27-9

Available Sizes

Curated Selection

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