P38? inhibitor 2
Product Specifications
CAS Number
1095003-80-7
Target
Others|||p38 MAPK
Related Pathways
MAPK|||Others
Bioactivity
P38? Inhibitor 2, a potent and selective inhibitor of p38? MAPK, exhibits a pIC50 value of 9.6. It also demonstrates inhibition of the hERG ion channel (IC50=27 ?M) and maintains promising selectivity, with <30% inhibition across a panel of 51 protein kinases at a 10 ?M concentration and a broad specificity against 141 other biological targets[1].
Smiles
CNCCOc1ccccc1C(C)(C)Nc1nccn(-c2cc(ccc2C)C(=O)NC2CC2)c1=O
Molecular Formula
C27H33N5O3
Molecular Weight
475.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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