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Tolmetin sodium dihydrate

Product Specifications

CAS Number

64490-92-2

Target

COX

Related Pathways

Immunology/Inflammation|||Neuroscience

Purity

0.9957

Bioactivity

Tolmetin sodium dihydrate is a potent non-steroidal anti-inflammatory drug (NSAID) that acts as an orally active cyclooxygenase (COX) inhibitor. Tolmetin sodium dihydrate demonstrates inhibitory concentration (IC50) values of 0.35 ?M and 0.82 ?M for human COX-1 and COX-2 enzymes, respectively, and is widely used as a reference compound for studying the biochemical and pharmacodynamic properties of NSAID-mediated prostaglandin synthesis inhibition.

Smiles

O=C(CC1=CC=C(N1C)C(C2=CC=C(C)C=C2)=O)[O-].[Na+].O.O

Molecular Formula

C15H18NNaO5

Molecular Weight

315.3

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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