Deacylcortivazol
Product Specifications
CAS Number
4906-84-7
Target
Others|||Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones|||Others
Bioactivity
Deacylcortivazol (DAC) is a potent glucocorticoid. When incubated with glucocorticoid-resistant mutants derived from the glucocorticoid-sensitive human leukemic cell line CEM-C7, DAC caused significant growth inhibition. The cytotoxicity of DAC at concentrations higher than necessary for glucocorticoid receptor saturation is not mediated by glucocorticoid receptors.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@](C(CO)=O)(O)[C@H](C)C4)[H])(C=C(C)C1=CC5=C(C2)C=NN5C6=CC=CC=C6)[H])[H]
Molecular Formula
C30H36N2O4
Molecular Weight
488.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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