Isoforskolin
Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS) -induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].
Product Specifications
CAS Number
[64657-21-2]
Product Name Alternative
Coleonol B
UNSPSC
12352005
Hazard Statement
H312
Target
Interleukin Related; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/isoforskolin.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@@]3([C@@]([C@@H](O)[C@@H](OC(C)=O)[C@@]1([H])C(C)(CC[C@@H]2O)C)(O[C@](C=C)(C)CC3=O)C)O
Molecular Formula
C22H34O7
Molecular Weight
410.50
Precautions
H312
References & Citations
Borrelia burgdorferi
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
IL-1; IL-6; IL-8; TNFRSF5/CD40
Available Sizes
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