Narasin (sodium salt)

Product Specifications

CAS Number

58331-17-2

Target

Parasite|||Apoptosis|||NF-?B|||Antibiotic|||Antibacterial

Related Pathways

Apoptosis|||Microbiology/Virology|||NF-?B

Bioactivity

Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL) -mediated apoptosis by ER stress in glioma cells and inhibits NF-?B signaling by suppressing the phosphorylation of I?B?.

Smiles

[Na+].CC[C@H]([C@@H]1O[C@@H]([C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@H]2O[C@@]3(O[C@@]4(CC[C@](C)(O4)[C@H]4CC[C@](O)(CC)[C@H](C)O4)[C@H](O)C=C3)[C@H](C)C[C@@H]2C)[C@@H](C)C[C@@H]1C)C([O-])=O