ELR510444

Product Specifications

CAS Number

1233948-35-0

Target

Apoptosis|||Microtubule Associated

Related Pathways

Cytoskeletal Signaling|||Apoptosis

Purity

0.9869

Bioactivity

ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ?III-tubulin-overexpressing cell lines.

Smiles

Cc1ccc(cc1)S(=O)(=O)Nc1cc(ccc1C)-c1ccc(s1)C#N

Molecular Formula

C19H16N2O2S2

Molecular Weight

368.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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