TC-S 7009
Product Specifications
CAS Number
1422955-31-4
Target
HIF/HIF Prolyl-Hydroxylase|||HIF
Related Pathways
Chromatin/Epigenetic|||Angiogenesis|||Metabolism
Purity
>99.99%
Bioactivity
TC-S 7009 is a potent and selective HIF-2? inhibitor (Kd: 81 nM) with significantly higher affinity for HIF-2? than HIF-1? (Kd >> 5?M) . TC-S 7009 disrupts HIF-2? heterodimerization, reduces HIF-2? target gene expression, and diminishes DNA binding activity.
Smiles
[O-][N+](=O)c1c(Nc2cc(F)cc(Cl)c2)ccc2nonc12
Molecular Formula
C12H6ClFN4O3
Molecular Weight
308.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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