GPP78
Product Specifications
Target
Autophagy|||NAMPT
Related Pathways
Metabolism|||Autophagy
Bioactivity
GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion) . GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells (IC50: 3.8 nM by inducing autophagy) . GPP78 has anti-cancer and anti-inflammatory effects.
Smiles
N(C(CCCCCCCN1C=C(N=N1)C=2C=CC=NC2)=O)C3=C(C=CC=C3)C4=CC=CC=C4
Molecular Formula
C27H29N5O
Molecular Weight
439.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/A75C3FE0-36AE-48F2-B4DD-1192E2C512CD/T15412
CAS Number
1202580-59-3
Available Sizes
Curated Selection
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