AG-024322

Product Specifications

CAS Number

837364-57-5

Target

COX|||Apoptosis|||CDK

Related Pathways

Neuroscience|||Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation

Purity

0.9853

Bioactivity

AG-024322 is a potent ATP-competitive inhibitor targeting pan-CDK, effectively inhibiting cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range (1-3 nM) .

Smiles

CCNCc1cncc(-c2ccc3[nH]nc(-c4nc5cc(F)cc(F)c5[nH]4)c3c2)c1C

Molecular Formula

C23H20F2N6

Molecular Weight

418.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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