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IRucaparib-AP6

Product Specifications

CAS Number

2410557-00-3

Target

PROTACs|||PARP

Related Pathways

Chromatin/Epigenetic|||DNA Damage/DNA Repair|||PROTAC

Bioactivity

IRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach.

Smiles

O=C1NCCC2=C(NC3=CC(F)=CC1=C32)C4=CC=C(C=C4)CN(C)CCOCCOCCOCCOCCOCCOCCNC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7

Molecular Formula

C46H55FN6O11

Molecular Weight

886.96

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/26DF1555-D127-484A-8E38-B54CC3499A5E/T13737

Available Sizes

Curated Selection

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