IRucaparib-AP6
Product Specifications
CAS Number
2410557-00-3
Target
PROTACs|||PARP
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair|||PROTAC
Bioactivity
IRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach.
Smiles
O=C1NCCC2=C(NC3=CC(F)=CC1=C32)C4=CC=C(C=C4)CN(C)CCOCCOCCOCCOCCOCCOCCNC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7
Molecular Formula
C46H55FN6O11
Molecular Weight
886.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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