TCMDC-135051
Product Specifications
CAS Number
2413716-15-9
Target
Others|||Parasite
Related Pathways
Microbiology/Virology|||Others
Purity
0.9905
Bioactivity
TCMDC-135051 is a potent and selective PfCLK3 protein kinase inhibitor demonstrating significant antiparasiticidal activity (EC50=320 nM) while exhibiting minimal off-target toxicity. It effectively hinders the transition from trophozoite to schizont, impairs transcription, and diminishes transmission to the mosquito vector.
Smiles
CCN(CC)Cc1ccc(OC)c(c1)-c1cc2c(ccnc2[nH]1)-c1ccc(C(O)=O)c(c1)C(C)C
Molecular Formula
C29H33N3O3
Molecular Weight
471.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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