Rilzabrutinib

1575596-29-0

EGFR|||HER|||BTK

Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

0.9976

Rilzabrutinib (PRN1008) is a reversible covalent, selective, and orally active inhibitor of Bruton's Tyrosine Kinase (BTK) with an IC50 of 1.3 nM.

CC(C)(\C=C(/C#N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)N1CCN(CC1)C1COC1

C36H40FN9O3

665.76

Cool pack

-20°C