INCB 3284 dimesylate

Product Specifications

CAS Number

887401-93-6

Target

Others|||CCR

Related Pathways

Others|||Immunology/Inflammation|||Microbiology/Virology|||GPCR/G Protein

Bioactivity

INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM) . It can be used in the research of acute liver failure.

Smiles

CS(=O)(O)=O.O[C@]1(C2=CN=C(OC)C=C2)CC[C@](N3C[C@@H](CC3)NC(CNC(C4=CC(C(F)(F)F)=CC=C4)=O)=O)([H])CC1.CS(=O)(O)=O

Molecular Formula

C28H39F3N4O10S2

Molecular Weight

712.76

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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