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CGP52411

Product Specifications

CAS Number

145915-58-8

Target

Beta Amyloid|||EGFR

Related Pathways

Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Neuroscience|||Angiogenesis

Purity

0.9978

Bioactivity

CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 ?M) . CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of ?-amyloid A?42 fibril aggregates. CGP52411 can be used in studies about Alzheimer's diseases.

Smiles

O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12

Molecular Formula

C20H15N3O2

Molecular Weight

329.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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