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BAY-985

Product Specifications

CAS Number

2409479-29-2

Target

I?B/IKK

Related Pathways

NF-?B

Purity

0.9962

Bioactivity

BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKK? (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKK?) with antitumor efficacy.

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C[C@@H](N1CCN(CC1)C(=O)CC(F)(F)F)c1ccnc(Nc2nc3ccc(cc3[nH]2)-c2cc(ncn2)N(C)C)c1

Molecular Formula

C27H30F3N9O

Molecular Weight

553.58

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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