Lactose

Lactose is a β-galactoside consisting of galactose and glucose residues, the main carbohydrate in mammalian breast milk. Lactose, a macronutrient and an inducer of host innate immune responses, possesses immune modulatory functions[1][2][3].

Product Specifications

CAS Number

[63-42-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; ERK; Interleukin Related; NF-κB

Type

Natural Products

Related Pathways

Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Lactose.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O[C@@H]([C@H](O)[C@@H](O)C=O)[C@H](O)CO)O1

Molecular Formula

C12H22O11

Molecular Weight

342.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Kleessen B, et al. Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr. 1997 May;65 (5) :1397-402.|[2]Pan LL, et al. Lactose Induces Phenotypic and Functional Changes of Neutrophils and Macrophages to Alleviate Acute Pancreatitis in Mice. Front Immunol. 2018 Apr 17;9:751.|[3]Paasela M, et al. Lactose inhibits regulatory T-cell-mediated suppression of effector T-cell interferon-γ and IL-17 production. Br J Nutr. 2014 Dec 14;112 (11) :1819-25.