Ochromycinone

Ochromycinone ((Rac) -STA-21) is a natural antibiotic and a STAT3 inhibitor. Ochromycinone can inhibits STAT3 DNA binding activity, STAT3 dimerization. Ochromycinone has anticancer and antimicrobial activity[1][2].

Product Specifications

CAS Number

[111540-00-2]

Product Name Alternative

(Rac) -STA-21

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial; STAT

Type

Natural Products

Related Pathways

Anti-infection; JAK/STAT Signaling; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/ochromycinone.html

Purity

98.29

Solubility

DMSO : 16.67 mg/mL (ultrasonic)

Smiles

CC(CC1=O)CC2=C1C3=C(C=C2)C(C4=C(O)C=CC=C4C3=O)=O

Molecular Formula

C19H14O4

Molecular Weight

306.31

Precautions

H302, H315, H319, H335

References & Citations

[1]Song H, et al. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci U S A. 2005 Mar 29;102 (13) :4700-5.|[2]Nataliya I. Kalinovskaya, et al. New Angucyclinones from the Marine Mollusk Associated Actinomycete Saccharothrix espanaensis An 113. Natural product communications. 2008, 3 (10) :1611-1616.