PSI

PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas[1].

Product Specifications

CAS Number

[158442-41-2]

Product Name Alternative

Proteasome Inhibitor 1; Z-Ile-Glu (OtBu) -Ala-Leu-CHO

UNSPSC

12352209

Target

Proteasome

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/psi.html

Purity

97.0

Solubility

H2O : < 0.1 mg/mL (adjust pH to 2 with Acetic acid)

Smiles

O=C([C@H]([C@@H](C)CC)NC(OCC1=CC=CC=C1)=O)N[C@@H](CCC(OC(C)(C)C)=O)C(N[C@@H](C)C(N[C@H](C=O)CC(C)C)=O)=O

Molecular Formula

C32H50N4O8

Molecular Weight

618.76

References & Citations

[1]Saji C, et al. Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells. Biochem Biophys Res Commun. 2011; 415 (4) :573-8.