(S) -mchm5U

(S) -mchm5U is a hydroxylated form of mcm5U, may be present in tRNA from the silkworm Bombyx mori. (S) -mchm5U may be present also in mammalian tRNA, and that the ALKBH8 oxygenase could be responsible for its formation. (S) -mchm5U can be used for RNA modification synthesis[1].

Product Specifications

CAS Number

[89665-83-8]

UNSPSC

12352005

Target

Drug Isomer

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-mchm5u.html

Purity

98.87

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

O=C(N(C=C1[C@@H](C(OC)=O)O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)NC1=O

Molecular Formula

C12H16N2O9

Molecular Weight

332.26

References & Citations

[1]van den Born E, et al. ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA. Nat Commun. 2011 Feb 1;2:172.