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MCC-DM1

Product Specifications

UNSPSC Description

MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues[1][2].

Target Antigen

Drug-Linker Conjugates for ADC

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mcc-dm1.html

Purity

99.52

Solubility

DMSO : 190 mg/mL (ultrasonic)

Smiles

C[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCSC5C(N(C(C5)=O)CC6CCC(CC6)C(N)=O)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1

Molecular Weight

974.55

References & Citations

[1]Manu Lopus, et al. Antibody-DM1 conjugates as cancer therapeutics. Cancer Lett. 2011 Aug 28;307(2):113-8.|[2]Liu Y, et al. LC-MS/MS method for the simultaneous determination of Lys-MCC-DM1, MCC-DM1 and DM1 as potential intracellular catabolites of the antibody-drug conjugate trastuzumab emtansine (T-DM1). J Pharm Biomed Anal. 2017 Apr 15;137:170-177.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-132250/MCC-DM1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-132250/MCC-DM1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1100692-14-5

Available Sizes

Curated Selection

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