Sortin1

Sortin1 is a vacuolar protein sorting inhibitor that targets carboxypeptidase Y (CPY) . Sortin1 is a soluble and membrane vacuolar marker molecule in plants and yeast[1].

Product Specifications

CAS Number

[503837-98-7]

UNSPSC

12352005

Target

Carboxypeptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Sortin1.html

Concentration

10mM

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(C)NC2=C(C(C3=C2C=CC=C3)=O)C1C4=CC=C(C5=CC=C(C(O)=O)C=C5)O4)OC

Molecular Formula

C26H19NO6

Molecular Weight

441.43

References & Citations

[1]Zouhar J, et al. Sorting inhibitors (Sortins) : Chemical compounds to study vacuolar sorting in Arabidopsis. Proc Natl Acad Sci U S A. 2004 Jun 22;101 (25) :9497-501.|[2]Rosado A, et al. Sortin1-hypersensitive mutants link vacuolar-trafficking defects and flavonoid metabolism in Arabidopsis vegetative tissues. Chem Biol. 2011 Feb 25;18 (2) :187-97.|[3]Orr DJ, et al. 1H NMR-based metabolomics methods for chemical genomics experiments. Methods Mol Biol. 2014;1056:225-39.|[4]Vásquez-Soto B, et al. Sortin2 enhances endocytic trafficking towards the vacuole in Saccharomyces cerevisiae. Biol Res. 2015 Jul 25;48 (1) :39.