Denopamine

Denopamine ((R) - (-) -Denopamine) is an orally active, selective β1-adrenergic agonist. Denopamine prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-α production in the heart. Cardiovascular effects[1].

Product Specifications

CAS Number

[71771-90-9]

Product Name Alternative

(R) - (-) -Denopamine; TA-064

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/denopamine.html

Purity

98.29

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=CC=C(C=C1)[C@H](CNCCC2=CC=C(C(OC)=C2)OC)O

Molecular Formula

C18H23NO4

Molecular Weight

317.38

Precautions

H302, H315, H319, H335

References & Citations

[1]R Nishio, et al. Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart. J Am Coll Cardiol. 1998 Sep;32 (3) :808-15.