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M190S

M109S is a novel small molecule protecting cells from mitochondria-dependent apoptosis both in vitro and in vivo. M109S has the potential to become a research tool for studying cell death mechanisms and to develop therapeutics targeting mitochondria-dependent cell death pathway. M109S has orally bioactivity with excellent brain permeability[1].

Product Specifications

CAS Number

[2578300-07-7]

UNSPSC

12352005

Target

Caspase

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m190s.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=NC(OC(C)=C2)=C2C(N[C@@H](C)C3=CC=C(C4=NC(C5CC5)=NO4)C=C3)=N1

Molecular Formula

C21H21N5O2

Molecular Weight

375.42

References & Citations

[1]Mieko Matsuyama, et al. Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death. Science 26, 107916, October 20, 2023

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Caspase 3

Available Sizes

Curated Selection

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