Apiin

Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells[1].

Product Specifications

CAS Number

[26544-34-3]

Product Name Alternative

Apigenin 7-O-apiosylglucoside; Apigenin 7- (2-O-apiosylglucoside)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/apiin.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO)[C@@H](O)[C@@H]3O)[C@@H]3O[C@@](OC[C@]4(O)CO)([H])[C@@H]4O)=C5)C2=C5O

Molecular Formula

C26H28O14

Molecular Weight

564.49

Precautions

H302, H315, H319, H335

References & Citations

[1]Mencherini T, et al. An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. J Pharm Pharmacol. 2007 Jun;59 (6) :891-7.